Anaplastic Large Cell Lymphoma

Anaplastic Large Cell Lymphoma (ALCL) is considered a high grade Non-Hodgkin’s Lymphoma (NHL) characterized by aggressive systemic disease. ALCL most commonly arises in children and young adults involving clonal expansion of T-cells.


FISH Assays:

ALK-BA: ALK translocations are observed in ~60% of ALCL cases. The most common fusion is NPM-ALK. Clinical trials for the treatment of ALCL with Crizotinib are being conducted.1

Order FISH Probes


    1. Duyster J, Bai RY, Morris SW. Translocations involving anaplastic lymphoma kinase (ALK). Oncogene. 2001 Sep 10;20(40):5623-37. Review. PubMed PMID: 11607814.